Amphotericin B liposome-induced acrocyanosis and elevated serum creatinine

A 77-year-old male patient developed acrocyanosis and pain after treatment with amphotericin B liposome 150 mg daily intravenously for disseminated histoplasmosis, and subsequently developed elevated serum creatinine. Amphotericin B liposome was discontinued, and anisodamine was used intravenously t...

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Autores principales: Zhang, Xiangcai, Jin, Jie, Cai, Chuang, Zheng, Ren, Wang, Yu, Xu, Yingying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Drug Watch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4900009/
https://www.ncbi.nlm.nih.gov/pubmed/27298506
http://dx.doi.org/10.4103/0253-7613.182889
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author Zhang, Xiangcai
Jin, Jie
Cai, Chuang
Zheng, Ren
Wang, Yu
Xu, Yingying
author_facet Zhang, Xiangcai
Jin, Jie
Cai, Chuang
Zheng, Ren
Wang, Yu
Xu, Yingying
author_sort Zhang, Xiangcai
collection PubMed
description A 77-year-old male patient developed acrocyanosis and pain after treatment with amphotericin B liposome 150 mg daily intravenously for disseminated histoplasmosis, and subsequently developed elevated serum creatinine. Amphotericin B liposome was discontinued, and anisodamine was used intravenously to treat acrocyanosis and pain induced by amphotericin B liposome for 9 days and patient was cured. Naranjo adverse drug reaction probability scale score was 5, the World Health Organization-Uppsala Monitoring Centre criteria: Probable, indicating a probable adverse reaction to amphotericin B liposome.
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spelling pubmed-49000092016-06-13 Amphotericin B liposome-induced acrocyanosis and elevated serum creatinine Zhang, Xiangcai Jin, Jie Cai, Chuang Zheng, Ren Wang, Yu Xu, Yingying Indian J Pharmacol Drug Watch A 77-year-old male patient developed acrocyanosis and pain after treatment with amphotericin B liposome 150 mg daily intravenously for disseminated histoplasmosis, and subsequently developed elevated serum creatinine. Amphotericin B liposome was discontinued, and anisodamine was used intravenously to treat acrocyanosis and pain induced by amphotericin B liposome for 9 days and patient was cured. Naranjo adverse drug reaction probability scale score was 5, the World Health Organization-Uppsala Monitoring Centre criteria: Probable, indicating a probable adverse reaction to amphotericin B liposome. Medknow Publications & Media Pvt Ltd 2016 /pmc/articles/PMC4900009/ /pubmed/27298506 http://dx.doi.org/10.4103/0253-7613.182889 Text en Copyright: © Indian Journal of Pharmacology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Drug Watch
Zhang, Xiangcai
Jin, Jie
Cai, Chuang
Zheng, Ren
Wang, Yu
Xu, Yingying
Amphotericin B liposome-induced acrocyanosis and elevated serum creatinine
title Amphotericin B liposome-induced acrocyanosis and elevated serum creatinine
title_full Amphotericin B liposome-induced acrocyanosis and elevated serum creatinine
title_fullStr Amphotericin B liposome-induced acrocyanosis and elevated serum creatinine
title_full_unstemmed Amphotericin B liposome-induced acrocyanosis and elevated serum creatinine
title_short Amphotericin B liposome-induced acrocyanosis and elevated serum creatinine
title_sort amphotericin b liposome-induced acrocyanosis and elevated serum creatinine
topic Drug Watch
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4900009/
https://www.ncbi.nlm.nih.gov/pubmed/27298506
http://dx.doi.org/10.4103/0253-7613.182889
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