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ER stress and the decline and fall of pancreatic beta cells in type 1 diabetes

Components of the unfolded protein response (UPR) modulate beta cell inflammation and death in early type 1 diabetes (T1D). The UPR is a mechanism by which cells react to the accumulation of misfolded proteins in the endoplasmic reticulum (ER). It aims to restore cellular homeostasis, but in case of...

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Detalles Bibliográficos
Autores principales:	Brozzi, Flora, Eizirik, Décio L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2016
Materias:	Review Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4900073/ https://www.ncbi.nlm.nih.gov/pubmed/26899404 http://dx.doi.org/10.3109/03009734.2015.1135217

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