Cargando…
Fit for the Eye: Aptamers in Ocular Disorders
For any new class of therapeutics, there are certain types of indications that represent a natural fit. For nucleic acid ligands in general, and aptamers in particular, the eye has historically been an attractive site for therapeutic intervention. In this review, we recount the discovery and early d...
Autores principales: | Drolet, Daniel W., Green, Louis S., Gold, Larry, Janjic, Nebojsa |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Mary Ann Liebert, Inc.
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4900223/ https://www.ncbi.nlm.nih.gov/pubmed/26757406 http://dx.doi.org/10.1089/nat.2015.0573 |
Ejemplares similares
-
Nucleic Acid Ligands With Protein-like Side Chains: Modified Aptamers and Their Use as Diagnostic and Therapeutic Agents
por: Rohloff, John C, et al.
Publicado: (2014) -
Chemically Modified Interleukin-6 Aptamer Inhibits Development of Collagen-Induced Arthritis in Cynomolgus Monkeys
por: Hirota, Masao, et al.
Publicado: (2016) -
Pharmacokinetic Properties of DNA Aptamers with Base Modifications
por: Gupta, Shashi, et al.
Publicado: (2017) -
Proteomic Profiles in Advanced Age-Related Macular Degeneration Using an Aptamer-Based Proteomic Technology
por: Lynch, Anne M., et al.
Publicado: (2019) -
Selection of DNA aptamers with two modified bases
por: Gawande, Bharat N., et al.
Publicado: (2017)