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Genomic study of adolescent idiopathic scoliosis in Japan
Adolescent idiopathic scoliosis (AIS) is a common disease. It is a multi-factorial (polygenic) disease controlled by genetic and environmental factors. Studies searching for genetic factors of AIS using linkage and association analyses have been conducted and several susceptibility genes have been r...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4900236/ https://www.ncbi.nlm.nih.gov/pubmed/27299157 http://dx.doi.org/10.1186/s13013-016-0067-x |
| _version_ | 1782436601784172544 |
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| author | Ikegawa, Shiro |
| author_facet | Ikegawa, Shiro |
| author_sort | Ikegawa, Shiro |
| collection | PubMed |
| description | Adolescent idiopathic scoliosis (AIS) is a common disease. It is a multi-factorial (polygenic) disease controlled by genetic and environmental factors. Studies searching for genetic factors of AIS using linkage and association analyses have been conducted and several susceptibility genes have been reported. This paper reviews the recent progress in the genome-wide association study of AIS in Japan and comments on its future task. |
| format | Online Article Text |
| id | pubmed-4900236 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2016 |
| publisher | BioMed Central |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-49002362016-06-13 Genomic study of adolescent idiopathic scoliosis in Japan Ikegawa, Shiro Scoliosis Spinal Disord Review Adolescent idiopathic scoliosis (AIS) is a common disease. It is a multi-factorial (polygenic) disease controlled by genetic and environmental factors. Studies searching for genetic factors of AIS using linkage and association analyses have been conducted and several susceptibility genes have been reported. This paper reviews the recent progress in the genome-wide association study of AIS in Japan and comments on its future task. BioMed Central 2016-04-01 /pmc/articles/PMC4900236/ /pubmed/27299157 http://dx.doi.org/10.1186/s13013-016-0067-x Text en © Ikegawa. 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
| spellingShingle | Review Ikegawa, Shiro Genomic study of adolescent idiopathic scoliosis in Japan |
| title | Genomic study of adolescent idiopathic scoliosis in Japan |
| title_full | Genomic study of adolescent idiopathic scoliosis in Japan |
| title_fullStr | Genomic study of adolescent idiopathic scoliosis in Japan |
| title_full_unstemmed | Genomic study of adolescent idiopathic scoliosis in Japan |
| title_short | Genomic study of adolescent idiopathic scoliosis in Japan |
| title_sort | genomic study of adolescent idiopathic scoliosis in japan |
| topic | Review |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4900236/ https://www.ncbi.nlm.nih.gov/pubmed/27299157 http://dx.doi.org/10.1186/s13013-016-0067-x |
| work_keys_str_mv | AT ikegawashiro genomicstudyofadolescentidiopathicscoliosisinjapan |