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Efficacy of tranexamic acid as compared to aprotinin in open heart surgery in children

BACKGROUND: Coagulopathy is a major issue in children undergoing high-risk pediatric cardiac surgery. Use of anti-fibrinolytics is well documented in adults, but recently there are questions raised about safety and effectiveness of their use on routine use. Tranexamic acid is a potent anti-fibrinoly...

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Detalles Bibliográficos
Autores principales: Muthialu, Nagarajan, Balakrishnan, Soundaravalli, Sundar, Rajani, Muralidharan, Srinivasan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4900320/
https://www.ncbi.nlm.nih.gov/pubmed/25566706
http://dx.doi.org/10.4103/0971-9784.148316