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Management of pulmonary alveolar proteinosis with whole lung lavage using extracorporeal membrane oxygenation support in a postrenal transplant patient with graft failure

Pulmonary alveolar proteinosis (PAP) is a rare lung disease characterized by accumulation of excessive lung surfactant in the alveoli leading to restrictive lung functions and impaired gas exchange. Whole lung lavage (WLL) is the treatment modality of choice, which is usually performed using double...

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Autores principales: Chauhan, Sandeep, Sharma, Kamal P., Bisoi, Akshay K., Pangeni, Raju, Madan, Karan, Chauhan, Yogendra S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4900367/
https://www.ncbi.nlm.nih.gov/pubmed/27052091
http://dx.doi.org/10.4103/0971-9784.179627
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author Chauhan, Sandeep
Sharma, Kamal P.
Bisoi, Akshay K.
Pangeni, Raju
Madan, Karan
Chauhan, Yogendra S.
author_facet Chauhan, Sandeep
Sharma, Kamal P.
Bisoi, Akshay K.
Pangeni, Raju
Madan, Karan
Chauhan, Yogendra S.
author_sort Chauhan, Sandeep
collection PubMed
description Pulmonary alveolar proteinosis (PAP) is a rare lung disease characterized by accumulation of excessive lung surfactant in the alveoli leading to restrictive lung functions and impaired gas exchange. Whole lung lavage (WLL) is the treatment modality of choice, which is usually performed using double lumen endobronchial tube insertion under general anesthesia and alternating unilateral lung ventilation and washing with normal saline. It may be difficult to perform WLL in patients with severe hypoxemia wherein patients do not tolerate single lung ventilation. Extracorporeal membrane oxygenation support (ECMO) has been used in such patients. We report a patient with autoimmune PAP following renal transplant who presented with marked hypoxemia and was managed by WLL under ECMO support.
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spelling pubmed-49003672016-06-16 Management of pulmonary alveolar proteinosis with whole lung lavage using extracorporeal membrane oxygenation support in a postrenal transplant patient with graft failure Chauhan, Sandeep Sharma, Kamal P. Bisoi, Akshay K. Pangeni, Raju Madan, Karan Chauhan, Yogendra S. Ann Card Anaesth Case Report Pulmonary alveolar proteinosis (PAP) is a rare lung disease characterized by accumulation of excessive lung surfactant in the alveoli leading to restrictive lung functions and impaired gas exchange. Whole lung lavage (WLL) is the treatment modality of choice, which is usually performed using double lumen endobronchial tube insertion under general anesthesia and alternating unilateral lung ventilation and washing with normal saline. It may be difficult to perform WLL in patients with severe hypoxemia wherein patients do not tolerate single lung ventilation. Extracorporeal membrane oxygenation support (ECMO) has been used in such patients. We report a patient with autoimmune PAP following renal transplant who presented with marked hypoxemia and was managed by WLL under ECMO support. Medknow Publications & Media Pvt Ltd 2016 /pmc/articles/PMC4900367/ /pubmed/27052091 http://dx.doi.org/10.4103/0971-9784.179627 Text en Copyright: © 2016 Annals of Cardiac Anaesthesia http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Case Report
Chauhan, Sandeep
Sharma, Kamal P.
Bisoi, Akshay K.
Pangeni, Raju
Madan, Karan
Chauhan, Yogendra S.
Management of pulmonary alveolar proteinosis with whole lung lavage using extracorporeal membrane oxygenation support in a postrenal transplant patient with graft failure
title Management of pulmonary alveolar proteinosis with whole lung lavage using extracorporeal membrane oxygenation support in a postrenal transplant patient with graft failure
title_full Management of pulmonary alveolar proteinosis with whole lung lavage using extracorporeal membrane oxygenation support in a postrenal transplant patient with graft failure
title_fullStr Management of pulmonary alveolar proteinosis with whole lung lavage using extracorporeal membrane oxygenation support in a postrenal transplant patient with graft failure
title_full_unstemmed Management of pulmonary alveolar proteinosis with whole lung lavage using extracorporeal membrane oxygenation support in a postrenal transplant patient with graft failure
title_short Management of pulmonary alveolar proteinosis with whole lung lavage using extracorporeal membrane oxygenation support in a postrenal transplant patient with graft failure
title_sort management of pulmonary alveolar proteinosis with whole lung lavage using extracorporeal membrane oxygenation support in a postrenal transplant patient with graft failure
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4900367/
https://www.ncbi.nlm.nih.gov/pubmed/27052091
http://dx.doi.org/10.4103/0971-9784.179627
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