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Cerebral oxygenation monitoring in patients with bilateral carotid stenosis undergoing urgent cardiac surgery: Observational case series

BACKGROUND: Patients with significant bilateral carotid artery stenosis requiring urgent cardiac surgery have an increased risk of stroke and death. The optimal management strategy remains inconclusive, and the available evidence does not support the superiority of one strategy over another. MATERIA...

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Autores principales: Aktuerk, Dincer, Mishra, Pankaj Kumar, Luckraz, Heyman, Garnham, Andrew, Khazi, Fayaz Mohammed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4900385/
https://www.ncbi.nlm.nih.gov/pubmed/26750675
http://dx.doi.org/10.4103/0971-9784.173021
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author Aktuerk, Dincer
Mishra, Pankaj Kumar
Luckraz, Heyman
Garnham, Andrew
Khazi, Fayaz Mohammed
author_facet Aktuerk, Dincer
Mishra, Pankaj Kumar
Luckraz, Heyman
Garnham, Andrew
Khazi, Fayaz Mohammed
author_sort Aktuerk, Dincer
collection PubMed
description BACKGROUND: Patients with significant bilateral carotid artery stenosis requiring urgent cardiac surgery have an increased risk of stroke and death. The optimal management strategy remains inconclusive, and the available evidence does not support the superiority of one strategy over another. MATERIALS AND METHODS: A number of noninvasive strategies have been developed for minimizing perioperative stroke including continuous real-time monitoring of cerebral oxygenation with near-infrared spectroscopy (NIRS). The number of patients presenting with this combination (bilateral significant carotid stenosis requiring urgent cardiac surgery) in any single institution will be small and hence there is a lack of large randomized studies. RESULTS: This case series describes our early experience with NIRS in a select group of patients with significant bilateral carotid stenosis undergoing urgent cardiac surgery (n = 8). In contrast to other studies, this series is a single surgeon, single center study, where the entire surgery (both distal ends and proximal ends) was performed during single aortic clamp technique, which effectively removes several confounding variables. NIRS monitoring led to the early recognition of decreased cerebral oxygenation, and corrective steps (increased cardiopulmonary bypass flow, increased pCO(2), etc.,) were taken. CONCLUSION: The study shows good clinical outcome with the use of NIRS. This is our “work in progress,” and we aim to conduct a larger study.
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spelling pubmed-49003852016-06-16 Cerebral oxygenation monitoring in patients with bilateral carotid stenosis undergoing urgent cardiac surgery: Observational case series Aktuerk, Dincer Mishra, Pankaj Kumar Luckraz, Heyman Garnham, Andrew Khazi, Fayaz Mohammed Ann Card Anaesth Original Article BACKGROUND: Patients with significant bilateral carotid artery stenosis requiring urgent cardiac surgery have an increased risk of stroke and death. The optimal management strategy remains inconclusive, and the available evidence does not support the superiority of one strategy over another. MATERIALS AND METHODS: A number of noninvasive strategies have been developed for minimizing perioperative stroke including continuous real-time monitoring of cerebral oxygenation with near-infrared spectroscopy (NIRS). The number of patients presenting with this combination (bilateral significant carotid stenosis requiring urgent cardiac surgery) in any single institution will be small and hence there is a lack of large randomized studies. RESULTS: This case series describes our early experience with NIRS in a select group of patients with significant bilateral carotid stenosis undergoing urgent cardiac surgery (n = 8). In contrast to other studies, this series is a single surgeon, single center study, where the entire surgery (both distal ends and proximal ends) was performed during single aortic clamp technique, which effectively removes several confounding variables. NIRS monitoring led to the early recognition of decreased cerebral oxygenation, and corrective steps (increased cardiopulmonary bypass flow, increased pCO(2), etc.,) were taken. CONCLUSION: The study shows good clinical outcome with the use of NIRS. This is our “work in progress,” and we aim to conduct a larger study. Medknow Publications & Media Pvt Ltd 2016 /pmc/articles/PMC4900385/ /pubmed/26750675 http://dx.doi.org/10.4103/0971-9784.173021 Text en Copyright: © 2016 Annals of Cardiac Anaesthesia http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Original Article
Aktuerk, Dincer
Mishra, Pankaj Kumar
Luckraz, Heyman
Garnham, Andrew
Khazi, Fayaz Mohammed
Cerebral oxygenation monitoring in patients with bilateral carotid stenosis undergoing urgent cardiac surgery: Observational case series
title Cerebral oxygenation monitoring in patients with bilateral carotid stenosis undergoing urgent cardiac surgery: Observational case series
title_full Cerebral oxygenation monitoring in patients with bilateral carotid stenosis undergoing urgent cardiac surgery: Observational case series
title_fullStr Cerebral oxygenation monitoring in patients with bilateral carotid stenosis undergoing urgent cardiac surgery: Observational case series
title_full_unstemmed Cerebral oxygenation monitoring in patients with bilateral carotid stenosis undergoing urgent cardiac surgery: Observational case series
title_short Cerebral oxygenation monitoring in patients with bilateral carotid stenosis undergoing urgent cardiac surgery: Observational case series
title_sort cerebral oxygenation monitoring in patients with bilateral carotid stenosis undergoing urgent cardiac surgery: observational case series
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4900385/
https://www.ncbi.nlm.nih.gov/pubmed/26750675
http://dx.doi.org/10.4103/0971-9784.173021
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