The ESX-5 System of Pathogenic Mycobacteria Is Involved In Capsule Integrity and Virulence through Its Substrate PPE10

Mycobacteria produce a capsule layer, which consists of glycan-like polysaccharides and a number of specific proteins. In this study, we show that, in slow-growing mycobacteria, the type VII secretion system ESX-5 plays a major role in the integrity and stability of the capsule. We have identified P...

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Detalles Bibliográficos
Autores principales: Ates, Louis S., van der Woude, Aniek D., Bestebroer, Jovanka, van Stempvoort, Gunny, Musters, René J. P., Garcia-Vallejo, Juan J., Picavet, Daisy I., van de Weerd, Robert, Maletta, Massimiliano, Kuijl, Coenraad P., van der Wel, Nicole N., Bitter, Wilbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4900558/
https://www.ncbi.nlm.nih.gov/pubmed/27280885
http://dx.doi.org/10.1371/journal.ppat.1005696

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