Dectin-3 Deficiency Promotes Colitis Development due to Impaired Antifungal Innate Immune Responses in the Gut

Interactions between commensal fungi and gut immune system are critical for establishing colonic homeostasis. Here we found that mice deficient in Dectin-3 (Clec4d (-/-)), a C-type lectin receptor that senses fungal infection, were more susceptible to dextran sodium sulfate (DSS)-induced colitis com...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Tingting, Pan, Deng, Zhou, Zhicheng, You, Yun, Jiang, Changying, Zhao, Xueqiang, Lin, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4900642/
https://www.ncbi.nlm.nih.gov/pubmed/27280399
http://dx.doi.org/10.1371/journal.ppat.1005662

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4900642/
https://www.ncbi.nlm.nih.gov/pubmed/27280399
http://dx.doi.org/10.1371/journal.ppat.1005662

Ejemplares similares