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RIPK3-Mediated Necroptosis and Apoptosis Contributes to Renal Tubular Cell Progressive Loss and Chronic Kidney Disease Progression in Rats

Tubulointerstitial fibrosis (TIF) is caused by the progressive loss of renal tubular cells and the consequent replacement of the extracellular matrix. The progressive depletion of renal tubular cells results from apoptosis and necroptosis; however, the relative significance of each of these cell dea...

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Detalles Bibliográficos
Autores principales: Zhu, Yongjun, Cui, Hongwang, Xia, Yunfeng, Gan, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4900656/
https://www.ncbi.nlm.nih.gov/pubmed/27281190
http://dx.doi.org/10.1371/journal.pone.0156729