Regulation of Smoothened Phosphorylation and High-Level Hedgehog Signaling Activity by a Plasma Membrane Associated Kinase

Hedgehog (Hh) signaling controls embryonic development and adult tissue homeostasis through the G protein coupled receptor (GPCR)-family protein Smoothened (Smo). Upon stimulation, Smo accumulates on the cell surface in Drosophila or primary cilia in vertebrates, which is thought to be essential for...

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Detalles Bibliográficos
Autores principales: Li, Shuangxi, Li, Shuang, Han, Yuhong, Tong, Chao, Wang, Bing, Chen, Yongbin, Jiang, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4900676/
https://www.ncbi.nlm.nih.gov/pubmed/27280464
http://dx.doi.org/10.1371/journal.pbio.1002481

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4900676/
https://www.ncbi.nlm.nih.gov/pubmed/27280464
http://dx.doi.org/10.1371/journal.pbio.1002481

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