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IFI16 Preferentially Binds to DNA with Quadruplex Structure and Enhances DNA Quadruplex Formation
Interferon-inducible protein 16 (IFI16) is a member of the HIN-200 protein family, containing two HIN domains and one PYRIN domain. IFI16 acts as a sensor of viral and bacterial DNA and is important for innate immune responses. IFI16 binds DNA and binding has been described to be DNA length-dependen...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4900677/ https://www.ncbi.nlm.nih.gov/pubmed/27280708 http://dx.doi.org/10.1371/journal.pone.0157156 |