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Protein translocation: what's the problem?

We came together in Leeds to commemorate and celebrate the life and achievements of Prof. Stephen Baldwin. For many years we, together with Sheena Radford and Roman Tuma (colleagues also of the University of Leeds), have worked together on the problem of protein translocation through the essential a...

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Detalles Bibliográficos
Autores principales: Corey, Robin A., Allen, William J., Collinson, Ian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4900745/
https://www.ncbi.nlm.nih.gov/pubmed/27284038
http://dx.doi.org/10.1042/BST20160047
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author Corey, Robin A.
Allen, William J.
Collinson, Ian
author_facet Corey, Robin A.
Allen, William J.
Collinson, Ian
author_sort Corey, Robin A.
collection PubMed
description We came together in Leeds to commemorate and celebrate the life and achievements of Prof. Stephen Baldwin. For many years we, together with Sheena Radford and Roman Tuma (colleagues also of the University of Leeds), have worked together on the problem of protein translocation through the essential and ubiquitous Sec system. Inspired and helped by Steve we may finally be making progress. My seminar described our latest hypothesis for the molecular mechanism of protein translocation, supported by results collected in Bristol and Leeds on the tractable bacterial secretion process–commonly known as the Sec system; work that will be published elsewhere. Below is a description of the alternative and contested models for protein translocation that we all have been contemplating for many years. This review will consider their pros and cons.
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spelling pubmed-49007452016-06-23 Protein translocation: what's the problem? Corey, Robin A. Allen, William J. Collinson, Ian Biochem Soc Trans Biochemical Society Focused Meetings We came together in Leeds to commemorate and celebrate the life and achievements of Prof. Stephen Baldwin. For many years we, together with Sheena Radford and Roman Tuma (colleagues also of the University of Leeds), have worked together on the problem of protein translocation through the essential and ubiquitous Sec system. Inspired and helped by Steve we may finally be making progress. My seminar described our latest hypothesis for the molecular mechanism of protein translocation, supported by results collected in Bristol and Leeds on the tractable bacterial secretion process–commonly known as the Sec system; work that will be published elsewhere. Below is a description of the alternative and contested models for protein translocation that we all have been contemplating for many years. This review will consider their pros and cons. Portland Press Ltd. 2016-06-09 2016-06-15 /pmc/articles/PMC4900745/ /pubmed/27284038 http://dx.doi.org/10.1042/BST20160047 Text en © 2016 The Author(s) http://creativecommons.org/licenses/by/4.0/ This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution Licence 4.0 (CC BY) (http://creativecommons.org/licenses/by/4.0/) .
spellingShingle Biochemical Society Focused Meetings
Corey, Robin A.
Allen, William J.
Collinson, Ian
Protein translocation: what's the problem?
title Protein translocation: what's the problem?
title_full Protein translocation: what's the problem?
title_fullStr Protein translocation: what's the problem?
title_full_unstemmed Protein translocation: what's the problem?
title_short Protein translocation: what's the problem?
title_sort protein translocation: what's the problem?
topic Biochemical Society Focused Meetings
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4900745/
https://www.ncbi.nlm.nih.gov/pubmed/27284038
http://dx.doi.org/10.1042/BST20160047
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