NADPH oxidase 4 protects against development of endothelial dysfunction and atherosclerosis in LDL receptor deficient mice

AIMS: Endothelial dysfunction is an early step in the development of atherosclerosis. Increased formation of superoxide anions by NADPH oxidase Nox1, 2, and 5 reduces nitric oxide availability and can promote endothelial dysfunction. In contrast, recent evidence supports a vasoprotective role of H(2...

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Detalles Bibliográficos
Autores principales: Langbein, Heike, Brunssen, Coy, Hofmann, Anja, Cimalla, Peter, Brux, Melanie, Bornstein, Stefan R., Deussen, Andreas, Koch, Edmund, Morawietz, Henning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Basic Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4900759/
https://www.ncbi.nlm.nih.gov/pubmed/26578199
http://dx.doi.org/10.1093/eurheartj/ehv564

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