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Allosteric modulation in monomers and oligomers of a G protein-coupled receptor

The M(2) muscarinic receptor is the prototypic model of allostery in GPCRs, yet the molecular and the supramolecular determinants of such effects are unknown. Monomers and oligomers of the M(2) muscarinic receptor therefore have been compared to identify those allosteric properties that are gained i...

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Detalles Bibliográficos
Autores principales:	Shivnaraine, Rabindra V, Kelly, Brendan, Sankar, Krishana S, Redka, Dar'ya S, Han, Yi Rang, Huang, Fei, Elmslie, Gwendolynne, Pinto, Daniel, Li, Yuchong, Rocheleau, Jonathan V, Gradinaru, Claudiu C, Ellis, John, Wells, James W
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2016
Materias:	Biochemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4900804/ https://www.ncbi.nlm.nih.gov/pubmed/27151542 http://dx.doi.org/10.7554/eLife.11685

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