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The role of nuclear imaging in multiple endocrine neoplasia 1 (MEN 1)
Multiple endocrine neoplasia 1 (MEN 1) is a rare genetic disorder classically characterized by a predisposition to tumors of the parathyroid glands, anterior pituitary gland, and pancreatic islet cells (1). In addition to exhibiting these characteristic tumors, MEN 1 patients also have an increased...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4901017/ https://www.ncbi.nlm.nih.gov/pubmed/27307880 http://dx.doi.org/10.2484/rcr.v5i4.452 |
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author | Wosnitzer, Brian Gadiraju, Ramesh |
author_facet | Wosnitzer, Brian Gadiraju, Ramesh |
author_sort | Wosnitzer, Brian |
collection | PubMed |
description | Multiple endocrine neoplasia 1 (MEN 1) is a rare genetic disorder classically characterized by a predisposition to tumors of the parathyroid glands, anterior pituitary gland, and pancreatic islet cells (1). In addition to exhibiting these characteristic tumors, MEN 1 patients also have an increased propensity for other tumors such as carcinoids, adrenal adenomas, angiofibromas, and lipomas (1, 2, 3). Although MEN 1 is rare, with a prevalence of approximately 2 per 100,000 people, recognition of this syndrome is extremely important for both patient treatment and evaluation of family members (1, 4). The tumors of MEN 1 are usually benign; however, malignancy of some carcinoid, islet cell, and gastrointestinal tract tumors can cause mortality (5, 6, 7, 8). Diagnosis of MEN 1 is usually made by a combination of history and physical examination, biochemical serum testing, and various imaging modalities (9, 10). We present a classic case of MEN 1 with unique presentation and diagnosis using predominantly nuclear imaging in order to emphasize the role of nuclear imaging in diagnosing and treating MEN 1. |
format | Online Article Text |
id | pubmed-4901017 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-49010172016-06-15 The role of nuclear imaging in multiple endocrine neoplasia 1 (MEN 1) Wosnitzer, Brian Gadiraju, Ramesh Radiol Case Rep Article Multiple endocrine neoplasia 1 (MEN 1) is a rare genetic disorder classically characterized by a predisposition to tumors of the parathyroid glands, anterior pituitary gland, and pancreatic islet cells (1). In addition to exhibiting these characteristic tumors, MEN 1 patients also have an increased propensity for other tumors such as carcinoids, adrenal adenomas, angiofibromas, and lipomas (1, 2, 3). Although MEN 1 is rare, with a prevalence of approximately 2 per 100,000 people, recognition of this syndrome is extremely important for both patient treatment and evaluation of family members (1, 4). The tumors of MEN 1 are usually benign; however, malignancy of some carcinoid, islet cell, and gastrointestinal tract tumors can cause mortality (5, 6, 7, 8). Diagnosis of MEN 1 is usually made by a combination of history and physical examination, biochemical serum testing, and various imaging modalities (9, 10). We present a classic case of MEN 1 with unique presentation and diagnosis using predominantly nuclear imaging in order to emphasize the role of nuclear imaging in diagnosing and treating MEN 1. Elsevier 2015-11-06 /pmc/articles/PMC4901017/ /pubmed/27307880 http://dx.doi.org/10.2484/rcr.v5i4.452 Text en © 2010 The Authors. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Article Wosnitzer, Brian Gadiraju, Ramesh The role of nuclear imaging in multiple endocrine neoplasia 1 (MEN 1) |
title | The role of nuclear imaging in multiple endocrine neoplasia 1 (MEN 1) |
title_full | The role of nuclear imaging in multiple endocrine neoplasia 1 (MEN 1) |
title_fullStr | The role of nuclear imaging in multiple endocrine neoplasia 1 (MEN 1) |
title_full_unstemmed | The role of nuclear imaging in multiple endocrine neoplasia 1 (MEN 1) |
title_short | The role of nuclear imaging in multiple endocrine neoplasia 1 (MEN 1) |
title_sort | role of nuclear imaging in multiple endocrine neoplasia 1 (men 1) |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4901017/ https://www.ncbi.nlm.nih.gov/pubmed/27307880 http://dx.doi.org/10.2484/rcr.v5i4.452 |
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