Development and Identification of a Novel Anti-HIV-1 Peptide Derived by Modification of the N-Terminal Domain of HIV-1 Integrase

The viral enzyme integrase (IN) is essential for the replication of human immunodeficiency virus type 1 (HIV-1) and represents an important target for the development of new antiretroviral drugs. In this study, we focused on the N-terminal domain (NTD), which is mainly involved into protein oligomer...

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Detalles Bibliográficos
Autores principales: Sala, Marina, Spensiero, Antonia, Esposito, Francesca, Scala, Maria C., Vernieri, Ermelinda, Bertamino, Alessia, Manfra, Michele, Carotenuto, Alfonso, Grieco, Paolo, Novellino, Ettore, Cadeddu, Marta, Tramontano, Enzo, Schols, Dominique, Campiglia, Pietro, Gomez-Monterrey, Isabel M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4901077/
https://www.ncbi.nlm.nih.gov/pubmed/27375570
http://dx.doi.org/10.3389/fmicb.2016.00845

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