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Visualizing K48 Ubiquitination during Presynaptic Formation By Ubiquitination-Induced Fluorescence Complementation (UiFC)

In recent years, signaling through ubiquitin has been shown to be of great importance for normal brain development. Indeed, fluctuations in ubiquitin levels and spontaneous mutations in (de)ubiquitination enzymes greatly perturb synapse formation and neuronal transmission. In the brain, expression o...

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Detalles Bibliográficos
Autores principales: Pinto, Maria J., Pedro, Joana R., Costa, Rui O., Almeida, Ramiro D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4901079/
https://www.ncbi.nlm.nih.gov/pubmed/27375430
http://dx.doi.org/10.3389/fnmol.2016.00043