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Pneumocystis pneumonia associated with human immunodeficiency virus infection without elevated (1 → 3)-β-D glucan: A case report

Pneumocystis pneumonia (PCP) caused by Pneumocystis jirovecii is one of the most common opportunistic infections in immunosuppressed patients, particularly in patients with acquired immunodeficiency syndrome (AIDS). (1 → 3)-β-D-glucan is a component of the cell wall of P. jirovecii and other fungi s...

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Detalles Bibliográficos
Autores principales: Kamada, Takahiro, Furuta, Kenjiro, Tomioka, Hiromi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4901181/
https://www.ncbi.nlm.nih.gov/pubmed/27330956
http://dx.doi.org/10.1016/j.rmcr.2016.04.005
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author Kamada, Takahiro
Furuta, Kenjiro
Tomioka, Hiromi
author_facet Kamada, Takahiro
Furuta, Kenjiro
Tomioka, Hiromi
author_sort Kamada, Takahiro
collection PubMed
description Pneumocystis pneumonia (PCP) caused by Pneumocystis jirovecii is one of the most common opportunistic infections in immunosuppressed patients, particularly in patients with acquired immunodeficiency syndrome (AIDS). (1 → 3)-β-D-glucan is a component of the cell wall of P. jirovecii and other fungi such as Candida sp., Aspergillus sp. and Histoplasma sp. The measurement of serum (1 → 3)-β-D-glucan has been reported to be a highly sensitive test for PCP related to human immunodeficiency virus (HIV-PCP). We report a case of HIV-PCP not associated with elevated serum (1 → 3)-β-D glucan and highlight how HIV-PCP cannot be completely ruled out if (1 → 3)-β-D glucan is negative.
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spelling pubmed-49011812016-06-21 Pneumocystis pneumonia associated with human immunodeficiency virus infection without elevated (1 → 3)-β-D glucan: A case report Kamada, Takahiro Furuta, Kenjiro Tomioka, Hiromi Respir Med Case Rep Case Report Pneumocystis pneumonia (PCP) caused by Pneumocystis jirovecii is one of the most common opportunistic infections in immunosuppressed patients, particularly in patients with acquired immunodeficiency syndrome (AIDS). (1 → 3)-β-D-glucan is a component of the cell wall of P. jirovecii and other fungi such as Candida sp., Aspergillus sp. and Histoplasma sp. The measurement of serum (1 → 3)-β-D-glucan has been reported to be a highly sensitive test for PCP related to human immunodeficiency virus (HIV-PCP). We report a case of HIV-PCP not associated with elevated serum (1 → 3)-β-D glucan and highlight how HIV-PCP cannot be completely ruled out if (1 → 3)-β-D glucan is negative. Elsevier 2016-04-30 /pmc/articles/PMC4901181/ /pubmed/27330956 http://dx.doi.org/10.1016/j.rmcr.2016.04.005 Text en © 2016 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Kamada, Takahiro
Furuta, Kenjiro
Tomioka, Hiromi
Pneumocystis pneumonia associated with human immunodeficiency virus infection without elevated (1 → 3)-β-D glucan: A case report
title Pneumocystis pneumonia associated with human immunodeficiency virus infection without elevated (1 → 3)-β-D glucan: A case report
title_full Pneumocystis pneumonia associated with human immunodeficiency virus infection without elevated (1 → 3)-β-D glucan: A case report
title_fullStr Pneumocystis pneumonia associated with human immunodeficiency virus infection without elevated (1 → 3)-β-D glucan: A case report
title_full_unstemmed Pneumocystis pneumonia associated with human immunodeficiency virus infection without elevated (1 → 3)-β-D glucan: A case report
title_short Pneumocystis pneumonia associated with human immunodeficiency virus infection without elevated (1 → 3)-β-D glucan: A case report
title_sort pneumocystis pneumonia associated with human immunodeficiency virus infection without elevated (1 → 3)-β-d glucan: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4901181/
https://www.ncbi.nlm.nih.gov/pubmed/27330956
http://dx.doi.org/10.1016/j.rmcr.2016.04.005
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