Cargando…

Sld3-MCM Interaction Facilitated by Dbf4-Dependent Kinase Defines an Essential Step in Eukaryotic DNA Replication Initiation

Sld3/Treslin is an evolutionarily conserved protein essential for activation of DNA helicase Mcm2-7 and replication initiation in all eukaryotes. Nevertheless, it remains elusive how Sld3 is recruited to origins. Here, we have identified the direct physical association of Sld3 with Mcm2 and Mcm6 sub...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fang, Dingqiang, Cao, Qinhong, Lou, Huiqiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2016
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4901202/ https://www.ncbi.nlm.nih.gov/pubmed/27375603 http://dx.doi.org/10.3389/fmicb.2016.00885

Ejemplares similares

Phosphopeptide binding by Sld3 links Dbf4‐dependent kinase to MCM replicative helicase activation
por: Deegan, Tom D, et al.
Publicado: (2016)

Dbf4 recruitment by forkhead transcription factors defines an upstream rate-limiting step in determining origin firing timing
por: Fang, Dingqiang, et al.
Publicado: (2017)

Concerted activities of Mcm4, Sld3, and Dbf4 in control of origin activation and DNA replication fork progression
por: Sheu, Yi-Jun, et al.
Publicado: (2016)

Checkpoint Dependent Inhibition of DNA Replication Initiation by Sld3 and Dbf4 Phosphorylation
por: Zegerman, Philip, et al.
Publicado: (2010)

Interactions of the Human MCM-BP Protein with MCM Complex Components and Dbf4
por: Nguyen, Tin, et al.
Publicado: (2012)

Structural Insight into the MCM double hexamer activation by Dbf4-Cdc7 kinase
por: Cheng, Jiaxuan, et al.
Publicado: (2022)

The Dbf4-Cdc7 kinase promotes S phase by alleviating an inhibitory activity in Mcm4
por: Sheu, Yi-Jun, et al.
Publicado: (2010)

Structural mechanism for the selective phosphorylation of DNA-loaded MCM double hexamers by the Dbf4-dependent kinase
por: Greiwe, Julia F., et al.
Publicado: (2021)

Author Correction: Structural Insight into the MCM double hexamer activation by Dbf4-Cdc7 kinase
por: Cheng, Jiaxuan, et al.
Publicado: (2022)

The structural basis of Cdc7-Dbf4 kinase dependent targeting and phosphorylation of the MCM2-7 double hexamer
por: Saleh, Almutasem, et al.
Publicado: (2022)

Ancient diversification of eukaryotic MCM DNA replication proteins
por: Liu, Yuan, et al.
Publicado: (2009)

How MCM loading and spreading specify eukaryotic DNA replication initiation sites
por: Hyrien, Olivier
Publicado: (2016)

MCM Paradox: Abundance of Eukaryotic Replicative Helicases and Genomic Integrity
por: Das, Mitali, et al.
Publicado: (2014)

Mcm10: A Dynamic Scaffold at Eukaryotic Replication Forks
por: Baxley, Ryan M., et al.
Publicado: (2017)

The Helicase Activity of Hyperthermophilic Archaeal MCM is Enhanced at High Temperatures by Lysine Methylation
por: Xia, Yisui, et al.
Publicado: (2015)

Nuclear DBF-2-related Kinases Are Essential Regulators of Cytokinesis in Bloodstream Stage Trypanosoma brucei
por: Ma, Jiangtao, et al.
Publicado: (2010)

Kinetochores Coordinate Pericentromeric Cohesion and Early DNA Replication by Cdc7-Dbf4 Kinase Recruitment
por: Natsume, Toyoaki, et al.
Publicado: (2013)

Archaeal MCM Proteins as an Analog for the Eukaryotic Mcm2–7 Helicase to Reveal Essential Features of Structure and Function
por: Miller, Justin M., et al.
Publicado: (2015)

Mcm8 and Mcm9 form a dimeric complex in Xenopus laevis egg extract that is not essential for DNA replication initiation
por: Gambus, Agnieszka, et al.
Publicado: (2013)

The role of CDK in the initiation step of DNA replication in eukaryotes
por: Tanaka, Seiji, et al.
Publicado: (2007)

A conserved MCM single-stranded DNA binding element is essential for replication initiation
por: Froelich, Clifford A, et al.
Publicado: (2014)

CDK phosphorylation of SLD-2 is required for replication initiation and germline development in C. elegans
por: Gaggioli, Vincent, et al.
Publicado: (2014)

CDK phosphorylation of SLD-2 is required for replication initiation and germline development in C. elegans
por: Gaggioli, Vincent, et al.
Publicado: (2014)

A Xenopus Dbf4 homolog is required for Cdc7 chromatin binding and DNA replication
por: Jares, Pedro, et al.
Publicado: (2004)

Cul4-Ddb1 ubiquitin ligases facilitate DNA replication-coupled sister chromatid cohesion through regulation of cohesin acetyltransferase Esco2
por: Sun, Haitao, et al.
Publicado: (2019)

Highlights of SLD physics
por: Zapalac, G H
Publicado: (1995)

Backgrounds at SLD 2000
por: Markiewicz, T W, et al.
Publicado: (1996)

Charm physics at SLD
por: De Groot, N
Publicado: (1998)

SLD design report
por: Stanford Linear Accelerator Center. Stanford
Publicado: (1984)

SLD Physics Week
por: Stanford Linear Accelerator Center. Stanford
Publicado: (1989)

The human GINS complex associates with Cdc45 and MCM and is essential for DNA replication
por: Aparicio, Tomás, et al.
Publicado: (2009)

Recruitment of Mcm10 to Sites of Replication Initiation Requires Direct Binding to the Minichromosome Maintenance (MCM) Complex
por: Douglas, Max E., et al.
Publicado: (2016)

Cdc7p-Dbf4p Regulates Mitotic Exit by Inhibiting Polo Kinase
por: Miller, Charles T., et al.
Publicado: (2009)

DNA translocation mechanism of the MCM complex and implications for replication initiation
por: Meagher, Martin, et al.
Publicado: (2019)

The SLD VXD3 detector and its initial performance
por: Suekane, F
Publicado: (1996)

Mck1 defines a key S-phase checkpoint effector in response to various degrees of replication threats
por: Li, Xiaoli, et al.
Publicado: (2019)

Stanford: Final SLD assembly
Publicado: (1989)

Updated measurement of the lifetime at SLD
por: Abe, K, et al.
Publicado: (1996)

B lifetimes and mixing with the SLD
por: Jaros, J A
Publicado: (1996)

Precision test at SLC/SLD
por: Kajikawa, R, et al.
Publicado: (1996)

Cannot write session to /tmp/vufind_sessions/sess_oa2mckmee088bv2q4k9v5e7bea