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Bilateral frosted branch angiitis as the presenting sign of antiphospholipid antibody syndrome

BACKGROUND: “Frosted branch retinal angiitis” is an encompassing term for a rare, typically bilateral diffuse retinal periphlebitis that may occur in a number of varying conditions. To our knowledge, we report the first case of frosted branch angiitis as the presenting sign of antiphospholipid antib...

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Autores principales: Wood, Edward H., Wong, Robert W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4901211/
https://www.ncbi.nlm.nih.gov/pubmed/27287993
http://dx.doi.org/10.1186/s12348-016-0089-9
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author Wood, Edward H.
Wong, Robert W.
author_facet Wood, Edward H.
Wong, Robert W.
author_sort Wood, Edward H.
collection PubMed
description BACKGROUND: “Frosted branch retinal angiitis” is an encompassing term for a rare, typically bilateral diffuse retinal periphlebitis that may occur in a number of varying conditions. To our knowledge, we report the first case of frosted branch angiitis as the presenting sign of antiphospholipid antibody syndrome in a 28-year-old woman. FINDINGS: This study is a retrospective case report and literature review. Serial fundus photos, fluorescein angiogram, and ocular coherence tomography taken were before and after treatment, showing resolution of diffuse retinal perivascular sheathing and macular edema along with marked improvement in visual acuity 4 months after the treatment with corticosteroids. CONCLUSIONS: Frosted branch angiitis can be seen in association with antiphospholipid antibody syndrome. Prompt recognition and treatment with corticosteroids may result in good visual prognosis, and long-term immunosuppression and additional anticoagulation may be beneficial to prevent recurrence.
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spelling pubmed-49012112016-06-27 Bilateral frosted branch angiitis as the presenting sign of antiphospholipid antibody syndrome Wood, Edward H. Wong, Robert W. J Ophthalmic Inflamm Infect Brief Report BACKGROUND: “Frosted branch retinal angiitis” is an encompassing term for a rare, typically bilateral diffuse retinal periphlebitis that may occur in a number of varying conditions. To our knowledge, we report the first case of frosted branch angiitis as the presenting sign of antiphospholipid antibody syndrome in a 28-year-old woman. FINDINGS: This study is a retrospective case report and literature review. Serial fundus photos, fluorescein angiogram, and ocular coherence tomography taken were before and after treatment, showing resolution of diffuse retinal perivascular sheathing and macular edema along with marked improvement in visual acuity 4 months after the treatment with corticosteroids. CONCLUSIONS: Frosted branch angiitis can be seen in association with antiphospholipid antibody syndrome. Prompt recognition and treatment with corticosteroids may result in good visual prognosis, and long-term immunosuppression and additional anticoagulation may be beneficial to prevent recurrence. Springer Berlin Heidelberg 2016-06-10 /pmc/articles/PMC4901211/ /pubmed/27287993 http://dx.doi.org/10.1186/s12348-016-0089-9 Text en © The Author(s). 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Brief Report
Wood, Edward H.
Wong, Robert W.
Bilateral frosted branch angiitis as the presenting sign of antiphospholipid antibody syndrome
title Bilateral frosted branch angiitis as the presenting sign of antiphospholipid antibody syndrome
title_full Bilateral frosted branch angiitis as the presenting sign of antiphospholipid antibody syndrome
title_fullStr Bilateral frosted branch angiitis as the presenting sign of antiphospholipid antibody syndrome
title_full_unstemmed Bilateral frosted branch angiitis as the presenting sign of antiphospholipid antibody syndrome
title_short Bilateral frosted branch angiitis as the presenting sign of antiphospholipid antibody syndrome
title_sort bilateral frosted branch angiitis as the presenting sign of antiphospholipid antibody syndrome
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4901211/
https://www.ncbi.nlm.nih.gov/pubmed/27287993
http://dx.doi.org/10.1186/s12348-016-0089-9
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