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Chromosome and Plasmids of the Tick-Borne Relapsing Fever Agent Borrelia hermsii

The zoonotic pathogen Borrelia hermsii bears its multiple paralogous genes for variable antigens on several linear plasmids. Application of combined long-read and short-read next-generation sequencing provided complete sequences for antigen-encoding plasmids as well as other linear and circular plas...

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Detalles Bibliográficos
Autor principal: Barbour, Alan G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4901232/
https://www.ncbi.nlm.nih.gov/pubmed/27284141
http://dx.doi.org/10.1128/genomeA.00528-16
Descripción
Sumario:The zoonotic pathogen Borrelia hermsii bears its multiple paralogous genes for variable antigens on several linear plasmids. Application of combined long-read and short-read next-generation sequencing provided complete sequences for antigen-encoding plasmids as well as other linear and circular plasmids and the linear chromosome of the genome.