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Dynein disruption perturbs post-synaptic components and contributes to impaired MuSK clustering at the NMJ: implication in ALS
The neuromuscular junction (NMJ) allows the transformation of a neuronal message into a mechanical force by muscle contraction and is the target of several neuromuscular disorders. While the neuronal side is under extensive research, the muscle appeared recently to have a growing role in the formati...
Autores principales: | Vilmont, Valérie, Cadot, Bruno, Vezin, Elsa, Le Grand, Fabien, Gomes, Edgar R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4901269/ https://www.ncbi.nlm.nih.gov/pubmed/27283349 http://dx.doi.org/10.1038/srep27804 |
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