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Predictive modeling targets thymidylate synthase ThyX in Mycobacterium tuberculosis

There is an urgent need to identify new treatments for tuberculosis (TB), a major infectious disease caused by Mycobacterium tuberculosis (Mtb), which results in 1.5 million deaths each year. We have targeted two essential enzymes in this organism that are promising for antibacterial therapy and rep...

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Detalles Bibliográficos
Autores principales:	Djaout, Kamel, Singh, Vinayak, Boum, Yap, Katawera, Victoria, Becker, Hubert F., Bush, Natassja G., Hearnshaw, Stephen J., Pritchard, Jennifer E., Bourbon, Pauline, Madrid, Peter B., Maxwell, Anthony, Mizrahi, Valerie, Myllykallio, Hannu, Ekins, Sean
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4901301/ https://www.ncbi.nlm.nih.gov/pubmed/27283217 http://dx.doi.org/10.1038/srep27792

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