Mycobacterium leprae-induced Insulin-like Growth Factor I attenuates antimicrobial mechanisms, promoting bacterial survival in macrophages

Mycobacterium leprae (ML), the etiologic agent of leprosy, can subvert macrophage antimicrobial activity by mechanisms that remain only partially understood. In the present study, the participation of hormone insulin-like growth factor I (IGF-I) in this phenomenum was investigated. Macrophages from...

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Detalles Bibliográficos
Autores principales: Batista-Silva, L. R., Rodrigues, Luciana Silva, Vivarini, Aislan de Carvalho, Costa, Fabrício da Mota Ramalho, Mattos, Katherine Antunes de, Costa, Maria Renata Sales Nogueira, Rosa, Patricia Sammarco, Toledo-Pinto, T. G., Dias, André Alves, Moura, Danielle Fonseca, Sarno, Euzenir Nunes, Lopes, Ulisses Gazos, Pessolani, Maria Cristina Vidal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4901318/
https://www.ncbi.nlm.nih.gov/pubmed/27282338
http://dx.doi.org/10.1038/srep27632

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