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p38 MAPK Inhibition Improves Synaptic Plasticity and Memory in Angiotensin II-dependent Hypertensive Mice

The pathogenesis of hypertension-related cognitive impairment has not been sufficiently clarified, new molecular targets are needed. p38 MAPK pathway plays an important role in hypertensive target organ damage. Activated p38 MAPK was seen in AD brain tissue. In this study, we found that long-term po...

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Detalles Bibliográficos
Autores principales: Dai, Hai-long, Hu, Wei-yuan, Jiang, Li-hong, Li, Le, Gaung, Xue-feng, Xiao, Zhi-cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4901328/
https://www.ncbi.nlm.nih.gov/pubmed/27283322
http://dx.doi.org/10.1038/srep27600