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Correlation of Apobec Mrna Expression with overall Survival and pd-l1 Expression in Urothelial Carcinoma
Metastatic urothelial carcinoma (mUC) has a very high mutational rate and is associated with an APOBEC mutation signature. We examined the correlation of APOBEC expression with overall survival (OS) and PD-L1 expression in a cohort of 73 mUC patients. mRNA expression of APOBEC3 family of genes (A3A,...
Autores principales: | Mullane, Stephanie A., Werner, Lillian, Rosenberg, Jonathan, Signoretti, Sabina, Callea, Marcella, Choueiri, Toni K., Freeman, Gordon J., Bellmunt, Joaquim |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4901342/ https://www.ncbi.nlm.nih.gov/pubmed/27283319 http://dx.doi.org/10.1038/srep27702 |
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