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Restoring Mitochondrial Function: A Small Molecule-mediated Approach to Enhance Glucose Stimulated Insulin Secretion in Cholesterol Accumulated Pancreatic beta cells

Dyslipidemia, particularly the elevated serum cholesterol levels, aggravate the pathophysiology of type 2 diabetes. In the present study we explored the relationship between fasting blood sugar and serum lipid parameters in human volunteers which revealed a significant linear effect of serum cholest...

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Detalles Bibliográficos
Autores principales: Asalla, Suman, Girada, Shravan Babu, Kuna, Ramya S., Chowdhury, Debabrata, Kandagatla, Bhaskar, Oruganti, Srinivas, Bhadra, Utpal, Bhadra, Manika Pal, Kalivendi, Shasi Vardhan, Rao, Swetha Pavani, Row, Anupama, Ibrahim, A, Ghosh, Partha Pratim, Mitra, Prasenjit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4901343/
https://www.ncbi.nlm.nih.gov/pubmed/27282931
http://dx.doi.org/10.1038/srep27513