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Nucleocytoplasmic human O-GlcNAc transferase is sufficient for O-GlcNAcylation of mitochondrial proteins

O-linked N-acetylglucosamine modification (O-GlcNAcylation) is a nutrient-dependent protein post-translational modification (PTM), dynamically and reversibly driven by two enzymes: O-GlcNAc transferase (OGT) and O-GlcNAcase (OGA) that catalyse the addition and the removal of the O-GlcNAc moieties to...

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Detalles Bibliográficos
Autores principales: Trapannone, Riccardo, Mariappa, Daniel, Ferenbach, Andrew T., vanAalten, Daan M.F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4901358/
https://www.ncbi.nlm.nih.gov/pubmed/27048592
http://dx.doi.org/10.1042/BCJ20160092