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Study design and data analysis considerations for the discovery of prognostic molecular biomarkers: a case study of progression free survival in advanced serous ovarian cancer

BACKGROUND: Accurate discovery of molecular biomarkers that are prognostic of a clinical outcome is an important yet challenging task, partly due to the combination of the typically weak genomic signal for a clinical outcome and the frequently strong noise due to microarray handling effects. Effecti...

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Detalles Bibliográficos
Autores principales:	Qin, Li-Xuan, Levine, Douglas A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4901402/ https://www.ncbi.nlm.nih.gov/pubmed/27282150 http://dx.doi.org/10.1186/s12920-016-0187-4

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