Functional genomics analyses of RNA-binding proteins reveal the splicing regulator SNRPB as an oncogenic candidate in glioblastoma

BACKGROUND: Glioblastoma (GBM) is the most common and aggressive type of brain tumor. Currently, GBM has an extremely poor outcome and there is no effective treatment. In this context, genomic and transcriptomic analyses have become important tools to identify new avenues for therapies. RNA-binding...

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Detalles Bibliográficos
Autores principales: Correa, Bruna R., de Araujo, Patricia Rosa, Qiao, Mei, Burns, Suzanne C., Chen, Chen, Schlegel, Richard, Agarwal, Seema, Galante, Pedro A. F., Penalva, Luiz O. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4901439/
https://www.ncbi.nlm.nih.gov/pubmed/27287018
http://dx.doi.org/10.1186/s13059-016-0990-4

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