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Outcome Following Isolated Osteochondral Allograft Transplantation of the Femoral Trochlea

OBJECTIVES: Osteochondral allograft (OCA) transplantation is a recognized treatment modality for cartilage damage in the knee. Few reports on outcomes of OCA in the patellofemoral joint and no reports on lesions isolated to the femoral trochlea are available. The goal of this study was to evaluate g...

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Autores principales: Cameron, James I., Pulido, Pamela, DeYoung, Allison, Gortz, Simon, Bugbee, William
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4901559/
http://dx.doi.org/10.1177/2325967115S00002
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author Cameron, James I.
Pulido, Pamela
DeYoung, Allison
Gortz, Simon
Bugbee, William
author_facet Cameron, James I.
Pulido, Pamela
DeYoung, Allison
Gortz, Simon
Bugbee, William
author_sort Cameron, James I.
collection PubMed
description OBJECTIVES: Osteochondral allograft (OCA) transplantation is a recognized treatment modality for cartilage damage in the knee. Few reports on outcomes of OCA in the patellofemoral joint and no reports on lesions isolated to the femoral trochlea are available. The goal of this study was to evaluate graft survivorship and clinical outcomes in patients who had an OCA of the femoral trochlea. METHODS: Twenty-nine knees in twenty-eight patients (mean age, 30. 2 years; range 12-47 years) were treated with fresh OCA transplant limited to the femoral trochlea. There were eight females and twenty males. Minimum follow-up was 2 years. The primary outcome was graft survivorship. Pain and function were assessed by the Modified Merle d’Aubigné-Postel (18-point) scale, Knee Injury and Osteoarthritis Outcome Score (KOOS), Knee Society function (KS-F), International Knee Documentation Committee (IKDC) and UCLA activity scores. The OCA patient satisfaction score (five point scale from extremely satisfied to extremely unsatisfied) was reported. RESULTS: Mean follow-up was 7.0 years (range 2.1-19.9 years) with 65.5% of patients with more than five years of follow-up. Graft survivorship was 91.7% at a mean of 7.0 years. One patient was converted to a total knee arthroplasty at 7.6 years after allograft surgery. Mean Modified Merle d’Aubigné-Postel (18-point) scale improved from 13.0 to 16.1, mean KS-F score from 65.6 to 85.2 and mean IKDC from 38.5 to 71.9. Mean UCLA score postoperatively was 7.9 and mean KOOS QOL (quality of life) scores improved from 34.0 preoperatively to 75.1 postoperatively. Eighty-nine percent of patients were extremely satisfied or satisfied with the outcome of surgery. CONCLUSION: Fresh OCA transplantation appears to have good results in this cohort of patients with advanced articular cartilage damage to the femoral trochlea. The procedure resulted in improved pain and function and could delay the need for patellofemoral or total knee arthroplasty for many years.
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spelling pubmed-49015592016-06-10 Outcome Following Isolated Osteochondral Allograft Transplantation of the Femoral Trochlea Cameron, James I. Pulido, Pamela DeYoung, Allison Gortz, Simon Bugbee, William Orthop J Sports Med Article OBJECTIVES: Osteochondral allograft (OCA) transplantation is a recognized treatment modality for cartilage damage in the knee. Few reports on outcomes of OCA in the patellofemoral joint and no reports on lesions isolated to the femoral trochlea are available. The goal of this study was to evaluate graft survivorship and clinical outcomes in patients who had an OCA of the femoral trochlea. METHODS: Twenty-nine knees in twenty-eight patients (mean age, 30. 2 years; range 12-47 years) were treated with fresh OCA transplant limited to the femoral trochlea. There were eight females and twenty males. Minimum follow-up was 2 years. The primary outcome was graft survivorship. Pain and function were assessed by the Modified Merle d’Aubigné-Postel (18-point) scale, Knee Injury and Osteoarthritis Outcome Score (KOOS), Knee Society function (KS-F), International Knee Documentation Committee (IKDC) and UCLA activity scores. The OCA patient satisfaction score (five point scale from extremely satisfied to extremely unsatisfied) was reported. RESULTS: Mean follow-up was 7.0 years (range 2.1-19.9 years) with 65.5% of patients with more than five years of follow-up. Graft survivorship was 91.7% at a mean of 7.0 years. One patient was converted to a total knee arthroplasty at 7.6 years after allograft surgery. Mean Modified Merle d’Aubigné-Postel (18-point) scale improved from 13.0 to 16.1, mean KS-F score from 65.6 to 85.2 and mean IKDC from 38.5 to 71.9. Mean UCLA score postoperatively was 7.9 and mean KOOS QOL (quality of life) scores improved from 34.0 preoperatively to 75.1 postoperatively. Eighty-nine percent of patients were extremely satisfied or satisfied with the outcome of surgery. CONCLUSION: Fresh OCA transplantation appears to have good results in this cohort of patients with advanced articular cartilage damage to the femoral trochlea. The procedure resulted in improved pain and function and could delay the need for patellofemoral or total knee arthroplasty for many years. SAGE Publications 2015-03-23 /pmc/articles/PMC4901559/ http://dx.doi.org/10.1177/2325967115S00002 Text en © The Author(s) 2015 http://creativecommons.org/licenses/by-nc-nd/3.0/ This open-access article is published and distributed under the Creative Commons Attribution - NonCommercial - No Derivatives License (http://creativecommons.org/licenses/by-nc-nd/3.0/), which permits the noncommercial use, distribution, and reproduction of the article in any medium, provided the original author and source are credited. You may not alter, transform, or build upon this article without the permission of the Author(s). For reprints and permission queries, please visit SAGE’s Web site at http://www.sagepub.com/journalsPermissions.nav.
spellingShingle Article
Cameron, James I.
Pulido, Pamela
DeYoung, Allison
Gortz, Simon
Bugbee, William
Outcome Following Isolated Osteochondral Allograft Transplantation of the Femoral Trochlea
title Outcome Following Isolated Osteochondral Allograft Transplantation of the Femoral Trochlea
title_full Outcome Following Isolated Osteochondral Allograft Transplantation of the Femoral Trochlea
title_fullStr Outcome Following Isolated Osteochondral Allograft Transplantation of the Femoral Trochlea
title_full_unstemmed Outcome Following Isolated Osteochondral Allograft Transplantation of the Femoral Trochlea
title_short Outcome Following Isolated Osteochondral Allograft Transplantation of the Femoral Trochlea
title_sort outcome following isolated osteochondral allograft transplantation of the femoral trochlea
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4901559/
http://dx.doi.org/10.1177/2325967115S00002
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