A convenient route to symmetrically and unsymmetrically substituted 3,5-diaryl-2,4,6-trimethylpyridines via Suzuki–Miyaura cross-coupling reaction

A series of differently substituted 3,5-diaryl-2,4,6-trimethylpyridines were prepared and characterized using the Suzuki–Miyaura coupling reaction with accordingly selected bromo-derivatives and arylboronic acids. The reaction conditions were carefully optimized allowing high yield of isolated produ...

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Autores principales: Błachut, Dariusz, Szawkało, Joanna, Czarnocki, Zbigniew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2016
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4901938/
https://www.ncbi.nlm.nih.gov/pubmed/27340474
http://dx.doi.org/10.3762/bjoc.12.82
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author Błachut, Dariusz
Szawkało, Joanna
Czarnocki, Zbigniew
author_facet Błachut, Dariusz
Szawkało, Joanna
Czarnocki, Zbigniew
author_sort Błachut, Dariusz
collection PubMed
description A series of differently substituted 3,5-diaryl-2,4,6-trimethylpyridines were prepared and characterized using the Suzuki–Miyaura coupling reaction with accordingly selected bromo-derivatives and arylboronic acids. The reaction conditions were carefully optimized allowing high yield of isolated products and also the construction of unsymmetrically substituted diarylpyridines, difficult to access by other methods.
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spelling pubmed-49019382016-06-23 A convenient route to symmetrically and unsymmetrically substituted 3,5-diaryl-2,4,6-trimethylpyridines via Suzuki–Miyaura cross-coupling reaction Błachut, Dariusz Szawkało, Joanna Czarnocki, Zbigniew Beilstein J Org Chem Full Research Paper A series of differently substituted 3,5-diaryl-2,4,6-trimethylpyridines were prepared and characterized using the Suzuki–Miyaura coupling reaction with accordingly selected bromo-derivatives and arylboronic acids. The reaction conditions were carefully optimized allowing high yield of isolated products and also the construction of unsymmetrically substituted diarylpyridines, difficult to access by other methods. Beilstein-Institut 2016-04-28 /pmc/articles/PMC4901938/ /pubmed/27340474 http://dx.doi.org/10.3762/bjoc.12.82 Text en Copyright © 2016, Błachut et al. https://creativecommons.org/licenses/by/2.0https://www.beilstein-journals.org/bjoc/termsThis is an Open Access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (https://www.beilstein-journals.org/bjoc/terms)
spellingShingle Full Research Paper
Błachut, Dariusz
Szawkało, Joanna
Czarnocki, Zbigniew
A convenient route to symmetrically and unsymmetrically substituted 3,5-diaryl-2,4,6-trimethylpyridines via Suzuki–Miyaura cross-coupling reaction
title A convenient route to symmetrically and unsymmetrically substituted 3,5-diaryl-2,4,6-trimethylpyridines via Suzuki–Miyaura cross-coupling reaction
title_full A convenient route to symmetrically and unsymmetrically substituted 3,5-diaryl-2,4,6-trimethylpyridines via Suzuki–Miyaura cross-coupling reaction
title_fullStr A convenient route to symmetrically and unsymmetrically substituted 3,5-diaryl-2,4,6-trimethylpyridines via Suzuki–Miyaura cross-coupling reaction
title_full_unstemmed A convenient route to symmetrically and unsymmetrically substituted 3,5-diaryl-2,4,6-trimethylpyridines via Suzuki–Miyaura cross-coupling reaction
title_short A convenient route to symmetrically and unsymmetrically substituted 3,5-diaryl-2,4,6-trimethylpyridines via Suzuki–Miyaura cross-coupling reaction
title_sort convenient route to symmetrically and unsymmetrically substituted 3,5-diaryl-2,4,6-trimethylpyridines via suzuki–miyaura cross-coupling reaction
topic Full Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4901938/
https://www.ncbi.nlm.nih.gov/pubmed/27340474
http://dx.doi.org/10.3762/bjoc.12.82
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