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Synthesis and in vitro cytotoxicity of acetylated 3-fluoro, 4-fluoro and 3,4-difluoro analogs of D-glucosamine and D-galactosamine

Background: Derivatives of D-glucosamine and D-galactosamine represent an important family of the cell surface glycan components and their fluorinated analogs found use as metabolic inhibitors of complex glycan biosynthesis, or as probes for the study of protein–carbohydrate interactions. This work...

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Detalles Bibliográficos
Autores principales: Horník, Štěpán, Červenková Šťastná, Lucie, Cuřínová, Petra, Sýkora, Jan, Káňová, Kateřina, Hrstka, Roman, Císařová, Ivana, Dračínský, Martin, Karban, Jindřich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4901990/
https://www.ncbi.nlm.nih.gov/pubmed/27340467
http://dx.doi.org/10.3762/bjoc.12.75