Recent advances in C(sp(3))–H bond functionalization via metal–carbene insertions

The recent development of intermolecular C–H insertion in the application of C(sp(3))–H bond functionalizations, especially for light alkanes, is reviewed. The challenging problem of regioselectivity in C–H bond insertions has been tackled by the use of sterically bulky metal catalysts, such as meta...

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Detalles Bibliográficos
Autores principales: Wang, Bo, Qiu, Di, Zhang, Yan, Wang, Jianbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2016
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4902055/
https://www.ncbi.nlm.nih.gov/pubmed/27340470
http://dx.doi.org/10.3762/bjoc.12.78
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author Wang, Bo
Qiu, Di
Zhang, Yan
Wang, Jianbo
author_facet Wang, Bo
Qiu, Di
Zhang, Yan
Wang, Jianbo
author_sort Wang, Bo
collection PubMed
description The recent development of intermolecular C–H insertion in the application of C(sp(3))–H bond functionalizations, especially for light alkanes, is reviewed. The challenging problem of regioselectivity in C–H bond insertions has been tackled by the use of sterically bulky metal catalysts, such as metal porphyrins and silver(I) complexes. In some cases, high regioselectivity and enantioselectivity have been achieved in the C–H bond insertion of small alkanes. This review highlights the most recent accomplishments in this field.
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spelling pubmed-49020552016-06-23 Recent advances in C(sp(3))–H bond functionalization via metal–carbene insertions Wang, Bo Qiu, Di Zhang, Yan Wang, Jianbo Beilstein J Org Chem Review The recent development of intermolecular C–H insertion in the application of C(sp(3))–H bond functionalizations, especially for light alkanes, is reviewed. The challenging problem of regioselectivity in C–H bond insertions has been tackled by the use of sterically bulky metal catalysts, such as metal porphyrins and silver(I) complexes. In some cases, high regioselectivity and enantioselectivity have been achieved in the C–H bond insertion of small alkanes. This review highlights the most recent accomplishments in this field. Beilstein-Institut 2016-04-25 /pmc/articles/PMC4902055/ /pubmed/27340470 http://dx.doi.org/10.3762/bjoc.12.78 Text en Copyright © 2016, Wang et al. https://creativecommons.org/licenses/by/2.0https://www.beilstein-journals.org/bjoc/termsThis is an Open Access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (https://www.beilstein-journals.org/bjoc/terms)
spellingShingle Review
Wang, Bo
Qiu, Di
Zhang, Yan
Wang, Jianbo
Recent advances in C(sp(3))–H bond functionalization via metal–carbene insertions
title Recent advances in C(sp(3))–H bond functionalization via metal–carbene insertions
title_full Recent advances in C(sp(3))–H bond functionalization via metal–carbene insertions
title_fullStr Recent advances in C(sp(3))–H bond functionalization via metal–carbene insertions
title_full_unstemmed Recent advances in C(sp(3))–H bond functionalization via metal–carbene insertions
title_short Recent advances in C(sp(3))–H bond functionalization via metal–carbene insertions
title_sort recent advances in c(sp(3))–h bond functionalization via metal–carbene insertions
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4902055/
https://www.ncbi.nlm.nih.gov/pubmed/27340470
http://dx.doi.org/10.3762/bjoc.12.78
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