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Simultaneous administration of high-dose atorvastatin and clopidogrel does not interfere with platelet inhibition during percutaneous coronary intervention

BACKGROUND: Reloading with high-dose atorvastatin shortly before percutaneous coronary interventions (PCIs) has been proposed as a strategy to reduce periprocedural myonecrosis. There has been a concern that statins that are metabolized by cytochrome P450 3A4 may interfere with clopidogrel metabolis...

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Detalles Bibliográficos
Autores principales:	Kreutz, Rolf P, Breall, Jeffrey A, Sinha, Anjan, von der Lohe, Elisabeth, Kovacs, Richard J, Flockhart, David A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2016
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4902146/ https://www.ncbi.nlm.nih.gov/pubmed/27350760 http://dx.doi.org/10.2147/CPAA.S98790

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