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Phosphorylations of Serines 21/9 in Glycogen Synthase Kinase 3α/β Are Not Required for Cell Lineage Commitment or WNT Signaling in the Normal Mouse Intestine

The WNT signalling pathway controls many developmental processes and plays a key role in maintenance of intestine renewal and homeostasis. Glycogen Synthase Kinase 3 (GSK3) is an important component of the WNT pathway and is involved in regulating β-catenin stability and expression of WNT target gen...

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Detalles Bibliográficos
Autores principales: Hey, Fiona, Giblett, Susan, Forrest, Stephanie, Herbert, Chelsea, Pritchard, Catrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4902192/
https://www.ncbi.nlm.nih.gov/pubmed/27284979
http://dx.doi.org/10.1371/journal.pone.0156877