Cargando…

The Transcriptional Repressor Gfi1 Plays a Critical Role in the Development of NKT1- and NKT2-Type iNKT Cells

Gfi1 plays an important role in the development and maintenance of many hematopoietic linage cells. However, the impact of Gfi1-deficiency on the iNKT cell differentiation remains unclear. We herein demonstrate a critical role of Gfi1 in regulating the development of iNKT cell subsets. In the thymus...

Descripción completa

Detalles Bibliográficos
Autores principales: Yasuoka, Toshiaki, Kuwahara, Makoto, Yamada, Takeshi, Maruyama, Saho, Suzuki, Junpei, Taniguchi, Masaru, Yasukawa, Masaki, Yamashita, Masakatsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4902269/
https://www.ncbi.nlm.nih.gov/pubmed/27284976
http://dx.doi.org/10.1371/journal.pone.0157395