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Inexpensive, serotype-independent protocol for native and bioengineered recombinant adeno-associated virus purification

Recombinant adeno-associated virus (AAV) is a valuable and often used gene therapy vector. With increased demand for highly purified virus comes the need for a standardized purification procedure that is applicable across many serotypes and includes bioengineered viruses. Currently cesium chloride b...

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Detalles Bibliográficos
Autores principales: Arden, Erik, Metzger, Joseph M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: jbm 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4902285/
https://www.ncbi.nlm.nih.gov/pubmed/27294171
http://dx.doi.org/10.14440/jbm.2016.102