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Experience of Intraoperative Cell Salvage in Surgical Correction of Spinal Deformity: A Retrospective Review of 124 Patients

The effect of intraoperative cell salvage (ICS) in surgical correction of spinal deformity remained controversial. This study was to quantitatively demonstrate its effect. In all, 124 patients having ICS in surgical correction of spinal deformity were included. These patients would be divided into 3...

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Autores principales: Yang, Changsheng, Wang, Jianru, Zheng, Zhaomin, Zhang, Zhongmin, Liu, Hui, Wang, Hua, Li, Zemin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4902333/
https://www.ncbi.nlm.nih.gov/pubmed/27227909
http://dx.doi.org/10.1097/MD.0000000000003339
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author Yang, Changsheng
Wang, Jianru
Zheng, Zhaomin
Zhang, Zhongmin
Liu, Hui
Wang, Hua
Li, Zemin
author_facet Yang, Changsheng
Wang, Jianru
Zheng, Zhaomin
Zhang, Zhongmin
Liu, Hui
Wang, Hua
Li, Zemin
author_sort Yang, Changsheng
collection PubMed
description The effect of intraoperative cell salvage (ICS) in surgical correction of spinal deformity remained controversial. This study was to quantitatively demonstrate its effect. In all, 124 patients having ICS in surgical correction of spinal deformity were included. These patients would be divided into 3 groups. Group 1—blood loss less than 15 mL/kg; group 2—between 15 and 37.5 mL/kg; and group 3—more than 37.5 mL/kg. The mean blood loss was 37.2 mL/kg and patients received 872.2 mL salvaged blood on average. The prevalence of intraoperative transfusion of allogenic RBC was 62.9% and the amount averaged 3.4 U. In groups 1 to 3, the prevalence of intraoperative allogenic transfusion was 23.5%, 66.7%, and 100%, respectively. Logistic analysis showed blood loss minus autotransfusion was of significance in predicting intraoperative transfusion, whereas the blood loss or autotransfusion alone was not, implicating an important role of ICS in saving allogenic RBC. The maximum decrease of hemoglobin after operation occurred in the third day, and the magnitude was 45.7 g/L. No severe complications related to ICS were observed. In summary, ICS could decrease the amount of allogenic transfusion in surgical correction of spinal deformity. However, in terms of reducing prevalence of allogenic transfusion, it had a protective effect only in patients with small blood loss.
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spelling pubmed-49023332016-06-23 Experience of Intraoperative Cell Salvage in Surgical Correction of Spinal Deformity: A Retrospective Review of 124 Patients Yang, Changsheng Wang, Jianru Zheng, Zhaomin Zhang, Zhongmin Liu, Hui Wang, Hua Li, Zemin Medicine (Baltimore) 7100 The effect of intraoperative cell salvage (ICS) in surgical correction of spinal deformity remained controversial. This study was to quantitatively demonstrate its effect. In all, 124 patients having ICS in surgical correction of spinal deformity were included. These patients would be divided into 3 groups. Group 1—blood loss less than 15 mL/kg; group 2—between 15 and 37.5 mL/kg; and group 3—more than 37.5 mL/kg. The mean blood loss was 37.2 mL/kg and patients received 872.2 mL salvaged blood on average. The prevalence of intraoperative transfusion of allogenic RBC was 62.9% and the amount averaged 3.4 U. In groups 1 to 3, the prevalence of intraoperative allogenic transfusion was 23.5%, 66.7%, and 100%, respectively. Logistic analysis showed blood loss minus autotransfusion was of significance in predicting intraoperative transfusion, whereas the blood loss or autotransfusion alone was not, implicating an important role of ICS in saving allogenic RBC. The maximum decrease of hemoglobin after operation occurred in the third day, and the magnitude was 45.7 g/L. No severe complications related to ICS were observed. In summary, ICS could decrease the amount of allogenic transfusion in surgical correction of spinal deformity. However, in terms of reducing prevalence of allogenic transfusion, it had a protective effect only in patients with small blood loss. Wolters Kluwer Health 2016-05-27 /pmc/articles/PMC4902333/ /pubmed/27227909 http://dx.doi.org/10.1097/MD.0000000000003339 Text en Copyright © 2016 Wolters Kluwer Health, Inc. All rights reserved. http://creativecommons.org/licenses/by-nc-nd/4.0 This is an open access article distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives License 4.0, where it is permissible to download, share and reproduce the work in any medium, provided it is properly cited. The work cannot be changed in any way or used commercially. http://creativecommons.org/licenses/by-nc-nd/4.0
spellingShingle 7100
Yang, Changsheng
Wang, Jianru
Zheng, Zhaomin
Zhang, Zhongmin
Liu, Hui
Wang, Hua
Li, Zemin
Experience of Intraoperative Cell Salvage in Surgical Correction of Spinal Deformity: A Retrospective Review of 124 Patients
title Experience of Intraoperative Cell Salvage in Surgical Correction of Spinal Deformity: A Retrospective Review of 124 Patients
title_full Experience of Intraoperative Cell Salvage in Surgical Correction of Spinal Deformity: A Retrospective Review of 124 Patients
title_fullStr Experience of Intraoperative Cell Salvage in Surgical Correction of Spinal Deformity: A Retrospective Review of 124 Patients
title_full_unstemmed Experience of Intraoperative Cell Salvage in Surgical Correction of Spinal Deformity: A Retrospective Review of 124 Patients
title_short Experience of Intraoperative Cell Salvage in Surgical Correction of Spinal Deformity: A Retrospective Review of 124 Patients
title_sort experience of intraoperative cell salvage in surgical correction of spinal deformity: a retrospective review of 124 patients
topic 7100
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4902333/
https://www.ncbi.nlm.nih.gov/pubmed/27227909
http://dx.doi.org/10.1097/MD.0000000000003339
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