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A Successfully Treated Metastatic Choriocarcinoma Coexistent With Pregnancy: A Case Report of a 4-Year Follow-Up
Gestational choriocarcinoma ended with a successful parturition is extremely rare, especially in cases where multiple metastases occurred. A 29-year-old Chinese primigravida was admitted with vaginal bleeding at 32(+2) gestational week, and diagnosed with gestational choriocarcinoma with vaginal, pu...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer Health
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4902341/ https://www.ncbi.nlm.nih.gov/pubmed/27227917 http://dx.doi.org/10.1097/MD.0000000000003505 |
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author | Yu, Panxi Diao, Wenqi Jiang, Xuefeng |
author_facet | Yu, Panxi Diao, Wenqi Jiang, Xuefeng |
author_sort | Yu, Panxi |
collection | PubMed |
description | Gestational choriocarcinoma ended with a successful parturition is extremely rare, especially in cases where multiple metastases occurred. A 29-year-old Chinese primigravida was admitted with vaginal bleeding at 32(+2) gestational week, and diagnosed with gestational choriocarcinoma with vaginal, pulmonary, and cerebral metastasis after pathological, and imaging examination. At 33(+1) gestational week, a healthy infant was delivered by cesarean section. Although no evidence of choriocarcinoma or any other forms of gestational trophoblastic diseases was found in the placenta and uterine curettages, the patient was given 7 cycles of postpartum chemotherapy. Her serum beta-human chorionic gonadotropin level fell to the normal range, and the metastatic lesions reduced. The baby is still free from diseases, and the patient reports no clinical manifestation 4 years after the hospital discharge. Despite its rapid metastases and complications, gestational choriocarcinoma still can be successfully treated by postpartum chemotherapy with the least delay. |
format | Online Article Text |
id | pubmed-4902341 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Wolters Kluwer Health |
record_format | MEDLINE/PubMed |
spelling | pubmed-49023412016-06-23 A Successfully Treated Metastatic Choriocarcinoma Coexistent With Pregnancy: A Case Report of a 4-Year Follow-Up Yu, Panxi Diao, Wenqi Jiang, Xuefeng Medicine (Baltimore) 5600 Gestational choriocarcinoma ended with a successful parturition is extremely rare, especially in cases where multiple metastases occurred. A 29-year-old Chinese primigravida was admitted with vaginal bleeding at 32(+2) gestational week, and diagnosed with gestational choriocarcinoma with vaginal, pulmonary, and cerebral metastasis after pathological, and imaging examination. At 33(+1) gestational week, a healthy infant was delivered by cesarean section. Although no evidence of choriocarcinoma or any other forms of gestational trophoblastic diseases was found in the placenta and uterine curettages, the patient was given 7 cycles of postpartum chemotherapy. Her serum beta-human chorionic gonadotropin level fell to the normal range, and the metastatic lesions reduced. The baby is still free from diseases, and the patient reports no clinical manifestation 4 years after the hospital discharge. Despite its rapid metastases and complications, gestational choriocarcinoma still can be successfully treated by postpartum chemotherapy with the least delay. Wolters Kluwer Health 2016-05-27 /pmc/articles/PMC4902341/ /pubmed/27227917 http://dx.doi.org/10.1097/MD.0000000000003505 Text en Copyright © 2016 Wolters Kluwer Health, Inc. All rights reserved. http://creativecommons.org/licenses/by/4.0 This is an open access article distributed under the Creative Commons Attribution License 4.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. http://creativecommons.org/licenses/by/4.0 |
spellingShingle | 5600 Yu, Panxi Diao, Wenqi Jiang, Xuefeng A Successfully Treated Metastatic Choriocarcinoma Coexistent With Pregnancy: A Case Report of a 4-Year Follow-Up |
title | A Successfully Treated Metastatic Choriocarcinoma Coexistent With Pregnancy: A Case Report of a 4-Year Follow-Up |
title_full | A Successfully Treated Metastatic Choriocarcinoma Coexistent With Pregnancy: A Case Report of a 4-Year Follow-Up |
title_fullStr | A Successfully Treated Metastatic Choriocarcinoma Coexistent With Pregnancy: A Case Report of a 4-Year Follow-Up |
title_full_unstemmed | A Successfully Treated Metastatic Choriocarcinoma Coexistent With Pregnancy: A Case Report of a 4-Year Follow-Up |
title_short | A Successfully Treated Metastatic Choriocarcinoma Coexistent With Pregnancy: A Case Report of a 4-Year Follow-Up |
title_sort | successfully treated metastatic choriocarcinoma coexistent with pregnancy: a case report of a 4-year follow-up |
topic | 5600 |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4902341/ https://www.ncbi.nlm.nih.gov/pubmed/27227917 http://dx.doi.org/10.1097/MD.0000000000003505 |
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