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Finger Fractures as an Early Manifestation of Primary Hyperparathyroidism Among Young Patients: A Case Report of a 30-Year-Old Male With Recurrent Osteoporotic Fractures

Osteoporosis and osteoporotic fractures represent a substantial health burden, and predominantly affect the elderly. Younger generations may also develop these conditions because of various predisposing conditions, including primary hyperparathyroidism. However, little information is available regar...

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Autores principales: Ozaki, Akihiko, Tanimoto, Tetsuya, Yamagishi, Eiki, Sato, Shunsuke, Tsukada, Manabu, Sawano, Toyoaki, Leppold, Claire, Tsuda, Kenji, Asakura, Takanori, Tsubokura, Masaharu, Kato, Shigeaki, Kami, Masahiro, Ohira, Hiromichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4902418/
https://www.ncbi.nlm.nih.gov/pubmed/27196476
http://dx.doi.org/10.1097/MD.0000000000003683
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author Ozaki, Akihiko
Tanimoto, Tetsuya
Yamagishi, Eiki
Sato, Shunsuke
Tsukada, Manabu
Sawano, Toyoaki
Leppold, Claire
Tsuda, Kenji
Asakura, Takanori
Tsubokura, Masaharu
Kato, Shigeaki
Kami, Masahiro
Ohira, Hiromichi
author_facet Ozaki, Akihiko
Tanimoto, Tetsuya
Yamagishi, Eiki
Sato, Shunsuke
Tsukada, Manabu
Sawano, Toyoaki
Leppold, Claire
Tsuda, Kenji
Asakura, Takanori
Tsubokura, Masaharu
Kato, Shigeaki
Kami, Masahiro
Ohira, Hiromichi
author_sort Ozaki, Akihiko
collection PubMed
description Osteoporosis and osteoporotic fractures represent a substantial health burden, and predominantly affect the elderly. Younger generations may also develop these conditions because of various predisposing conditions, including primary hyperparathyroidism. However, little information is available regarding early skeletal manifestations of primary hyperparathyroidism. A 30-year-old Japanese male presented with pain in his left wrist, and was diagnosed with a distal radius fracture. During surgery, we noticed decreased bone strength of the fracture site. Further investigation found osteoporosis and primary hyperparathyroidism owing to a solitary parathyroid adenoma, which was resected without significant complications. History revealed that the patient suffered a metacarpal bone fracture of his right fifth bone 6 months earlier. Although serial x-rays at that time had shown rapidly developed cortical bone erosion around the fractured finger, the possibility of primary hyperparathyroidism was overlooked because of poor awareness of the condition, leading to a 6-month delay in the diagnosis of primary hyperparathyroidism. Clinicians should be aware that finger fractures may be an early skeletal manifestation of primary hyperparathyroidism that can help achieve a prompt diagnosis of the condition, especially when they occur in young adults in the absence of major trauma.
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spelling pubmed-49024182016-06-23 Finger Fractures as an Early Manifestation of Primary Hyperparathyroidism Among Young Patients: A Case Report of a 30-Year-Old Male With Recurrent Osteoporotic Fractures Ozaki, Akihiko Tanimoto, Tetsuya Yamagishi, Eiki Sato, Shunsuke Tsukada, Manabu Sawano, Toyoaki Leppold, Claire Tsuda, Kenji Asakura, Takanori Tsubokura, Masaharu Kato, Shigeaki Kami, Masahiro Ohira, Hiromichi Medicine (Baltimore) 4300 Osteoporosis and osteoporotic fractures represent a substantial health burden, and predominantly affect the elderly. Younger generations may also develop these conditions because of various predisposing conditions, including primary hyperparathyroidism. However, little information is available regarding early skeletal manifestations of primary hyperparathyroidism. A 30-year-old Japanese male presented with pain in his left wrist, and was diagnosed with a distal radius fracture. During surgery, we noticed decreased bone strength of the fracture site. Further investigation found osteoporosis and primary hyperparathyroidism owing to a solitary parathyroid adenoma, which was resected without significant complications. History revealed that the patient suffered a metacarpal bone fracture of his right fifth bone 6 months earlier. Although serial x-rays at that time had shown rapidly developed cortical bone erosion around the fractured finger, the possibility of primary hyperparathyroidism was overlooked because of poor awareness of the condition, leading to a 6-month delay in the diagnosis of primary hyperparathyroidism. Clinicians should be aware that finger fractures may be an early skeletal manifestation of primary hyperparathyroidism that can help achieve a prompt diagnosis of the condition, especially when they occur in young adults in the absence of major trauma. Wolters Kluwer Health 2016-05-20 /pmc/articles/PMC4902418/ /pubmed/27196476 http://dx.doi.org/10.1097/MD.0000000000003683 Text en Copyright © 2016 Wolters Kluwer Health, Inc. All rights reserved. http://creativecommons.org/licenses/by/4.0 This is an open access article distributed under the Creative Commons Attribution License 4.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. http://creativecommons.org/licenses/by/4.0
spellingShingle 4300
Ozaki, Akihiko
Tanimoto, Tetsuya
Yamagishi, Eiki
Sato, Shunsuke
Tsukada, Manabu
Sawano, Toyoaki
Leppold, Claire
Tsuda, Kenji
Asakura, Takanori
Tsubokura, Masaharu
Kato, Shigeaki
Kami, Masahiro
Ohira, Hiromichi
Finger Fractures as an Early Manifestation of Primary Hyperparathyroidism Among Young Patients: A Case Report of a 30-Year-Old Male With Recurrent Osteoporotic Fractures
title Finger Fractures as an Early Manifestation of Primary Hyperparathyroidism Among Young Patients: A Case Report of a 30-Year-Old Male With Recurrent Osteoporotic Fractures
title_full Finger Fractures as an Early Manifestation of Primary Hyperparathyroidism Among Young Patients: A Case Report of a 30-Year-Old Male With Recurrent Osteoporotic Fractures
title_fullStr Finger Fractures as an Early Manifestation of Primary Hyperparathyroidism Among Young Patients: A Case Report of a 30-Year-Old Male With Recurrent Osteoporotic Fractures
title_full_unstemmed Finger Fractures as an Early Manifestation of Primary Hyperparathyroidism Among Young Patients: A Case Report of a 30-Year-Old Male With Recurrent Osteoporotic Fractures
title_short Finger Fractures as an Early Manifestation of Primary Hyperparathyroidism Among Young Patients: A Case Report of a 30-Year-Old Male With Recurrent Osteoporotic Fractures
title_sort finger fractures as an early manifestation of primary hyperparathyroidism among young patients: a case report of a 30-year-old male with recurrent osteoporotic fractures
topic 4300
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4902418/
https://www.ncbi.nlm.nih.gov/pubmed/27196476
http://dx.doi.org/10.1097/MD.0000000000003683
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