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Periodontal Treatment Reduces Risk of Adverse Respiratory Events in Patients With Chronic Obstructive Pulmonary Disease: A Propensity-Matched Cohort Study

Treatment of periodontal diseases has been associated with benefit outcomes for patients with chronic obstructive pulmonary disease (COPD). However, no population-based cohort study has been conducted. We evaluated this relationship by retrospective cohort study using a large population data. Using...

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Autores principales: Shen, Te-Chun, Chang, Pei-Ying, Lin, Cheng-Li, Chen, Chia-Hung, Tu, Chih-Yen, Hsia, Te-Chun, Shih, Chuen-Ming, Hsu, Wu-Huei, Sung, Fung-Chang, Kao, Chia-Hung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4902439/
https://www.ncbi.nlm.nih.gov/pubmed/27196497
http://dx.doi.org/10.1097/MD.0000000000003735
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author Shen, Te-Chun
Chang, Pei-Ying
Lin, Cheng-Li
Chen, Chia-Hung
Tu, Chih-Yen
Hsia, Te-Chun
Shih, Chuen-Ming
Hsu, Wu-Huei
Sung, Fung-Chang
Kao, Chia-Hung
author_facet Shen, Te-Chun
Chang, Pei-Ying
Lin, Cheng-Li
Chen, Chia-Hung
Tu, Chih-Yen
Hsia, Te-Chun
Shih, Chuen-Ming
Hsu, Wu-Huei
Sung, Fung-Chang
Kao, Chia-Hung
author_sort Shen, Te-Chun
collection PubMed
description Treatment of periodontal diseases has been associated with benefit outcomes for patients with chronic obstructive pulmonary disease (COPD). However, no population-based cohort study has been conducted. We evaluated this relationship by retrospective cohort study using a large population data. Using the National Health Insurance claims data of Taiwan, we identified 5562 COPD patients with periodontal diseases who had received periodontal treatment as the treatment group. The comparison group was selected at a 1:1 ratio matched by the propensity score estimated with age, sex, date of COPD diagnosis and periodontal treatment, and comorbidities. Both groups were followed up for 5 years to compare risks of acute exacerbation, pneumonia, and acute respiratory failure. The incidence rates of adverse respiratory events were significantly lower in the treatment group than in the comparison group: 3.79 versus 4.21 per 100 person-years for emergency room visits, 2.75 versus 3.65 per 100 person-years for hospitalizations, and 0.66 versus 0.75 per 100 person-years for intensive care unit admissions. The treatment group also had a 37% reduced risk of deaths (1.81 vs 2.87 per 100 person-years), with an adjusted hazard ratio of 0.57 (95% confidence interval 0.52–0.62). Periodontal treatment for COPD patients could reduce the risk of adverse respiratory events and mortality. The adequate periodontal health care is important for COPD patients with periodontal diseases.
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spelling pubmed-49024392016-06-23 Periodontal Treatment Reduces Risk of Adverse Respiratory Events in Patients With Chronic Obstructive Pulmonary Disease: A Propensity-Matched Cohort Study Shen, Te-Chun Chang, Pei-Ying Lin, Cheng-Li Chen, Chia-Hung Tu, Chih-Yen Hsia, Te-Chun Shih, Chuen-Ming Hsu, Wu-Huei Sung, Fung-Chang Kao, Chia-Hung Medicine (Baltimore) 4400 Treatment of periodontal diseases has been associated with benefit outcomes for patients with chronic obstructive pulmonary disease (COPD). However, no population-based cohort study has been conducted. We evaluated this relationship by retrospective cohort study using a large population data. Using the National Health Insurance claims data of Taiwan, we identified 5562 COPD patients with periodontal diseases who had received periodontal treatment as the treatment group. The comparison group was selected at a 1:1 ratio matched by the propensity score estimated with age, sex, date of COPD diagnosis and periodontal treatment, and comorbidities. Both groups were followed up for 5 years to compare risks of acute exacerbation, pneumonia, and acute respiratory failure. The incidence rates of adverse respiratory events were significantly lower in the treatment group than in the comparison group: 3.79 versus 4.21 per 100 person-years for emergency room visits, 2.75 versus 3.65 per 100 person-years for hospitalizations, and 0.66 versus 0.75 per 100 person-years for intensive care unit admissions. The treatment group also had a 37% reduced risk of deaths (1.81 vs 2.87 per 100 person-years), with an adjusted hazard ratio of 0.57 (95% confidence interval 0.52–0.62). Periodontal treatment for COPD patients could reduce the risk of adverse respiratory events and mortality. The adequate periodontal health care is important for COPD patients with periodontal diseases. Wolters Kluwer Health 2016-05-20 /pmc/articles/PMC4902439/ /pubmed/27196497 http://dx.doi.org/10.1097/MD.0000000000003735 Text en Copyright © 2016 Wolters Kluwer Health, Inc. All rights reserved. http://creativecommons.org/licenses/by-nc/4.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial License 4.0 (CCBY-NC), where it is permissible to download, share, remix, transform, and buildup the work provided it is properly cited. The work cannot be used commercially. http://creativecommons.org/licenses/by-nc/4.0
spellingShingle 4400
Shen, Te-Chun
Chang, Pei-Ying
Lin, Cheng-Li
Chen, Chia-Hung
Tu, Chih-Yen
Hsia, Te-Chun
Shih, Chuen-Ming
Hsu, Wu-Huei
Sung, Fung-Chang
Kao, Chia-Hung
Periodontal Treatment Reduces Risk of Adverse Respiratory Events in Patients With Chronic Obstructive Pulmonary Disease: A Propensity-Matched Cohort Study
title Periodontal Treatment Reduces Risk of Adverse Respiratory Events in Patients With Chronic Obstructive Pulmonary Disease: A Propensity-Matched Cohort Study
title_full Periodontal Treatment Reduces Risk of Adverse Respiratory Events in Patients With Chronic Obstructive Pulmonary Disease: A Propensity-Matched Cohort Study
title_fullStr Periodontal Treatment Reduces Risk of Adverse Respiratory Events in Patients With Chronic Obstructive Pulmonary Disease: A Propensity-Matched Cohort Study
title_full_unstemmed Periodontal Treatment Reduces Risk of Adverse Respiratory Events in Patients With Chronic Obstructive Pulmonary Disease: A Propensity-Matched Cohort Study
title_short Periodontal Treatment Reduces Risk of Adverse Respiratory Events in Patients With Chronic Obstructive Pulmonary Disease: A Propensity-Matched Cohort Study
title_sort periodontal treatment reduces risk of adverse respiratory events in patients with chronic obstructive pulmonary disease: a propensity-matched cohort study
topic 4400
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4902439/
https://www.ncbi.nlm.nih.gov/pubmed/27196497
http://dx.doi.org/10.1097/MD.0000000000003735
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