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Nicotinamide Phosphoribosyltransferase Attenuates Methotrexate Response in Juvenile Idiopathic Arthritis and In Vitro

Variability in response to methotrexate (MTX) in the treatment of juvenile idiopathic arthritis (JIA) remains unpredictable and poorly understood. Based on previous studies implicating an interaction between nicotinamide phosphoribosyltransferase (NAMPT) expression and MTX therapy in inflammatory ar...

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Detalles Bibliográficos
Autores principales: Funk, RS, Singh, R, Pramann, L, Gigliotti, N, Islam, S, Heruth, DP, Ye, SQ, Chan, MA, Leeder, JS, Becker, ML
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4902726/
https://www.ncbi.nlm.nih.gov/pubmed/27166432
http://dx.doi.org/10.1111/cts.12399