Pharmacological Modulation of Calcium Homeostasis in Familial Dilated Cardiomyopathy: An In Vitro Analysis From an RBM20 Patient‐Derived iPSC Model

For inherited cardiomyopathies, abnormal sensitivity to intracellular calcium (Ca(2+)), incurred from genetic mutations, initiates subsequent molecular events leading to pathological remodeling. Here, we characterized the effect of β‐adrenergic stress in familial dilated cardiomyopathy (DCM) using h...

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Detalles Bibliográficos
Autores principales: Wyles, SP, Hrstka, SC, Reyes, S, Terzic, A, Olson, TM, Nelson, TJ
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4902766/
https://www.ncbi.nlm.nih.gov/pubmed/27105042
http://dx.doi.org/10.1111/cts.12393

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4902766/
https://www.ncbi.nlm.nih.gov/pubmed/27105042
http://dx.doi.org/10.1111/cts.12393

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