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Assessment of repeatability and treatment response in early phase clinical trials using DCE-MRI: comparison of parametric analysis using MR- and CT-derived arterial input functions

OBJECTIVES: Pharmacokinetic (PK) modelling of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) data requires a reliable measure of the arterial input function (AIF) to robustly characterise tumour vascular properties. This study compared repeatability and treatment-response effects of...

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Detalles Bibliográficos
Autores principales:	Rata, Mihaela, Collins, David J., Darcy, James, Messiou, Christina, Tunariu, Nina, Desouza, Nandita, Young, Helen, Leach, Martin O., Orton, Matthew R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2015
Materias:	Magnetic Resonance
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4902841/ https://www.ncbi.nlm.nih.gov/pubmed/26385804 http://dx.doi.org/10.1007/s00330-015-4012-9

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