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Effects of striatal transplantation of cells transfected with GDNF gene without pre- and pro-regions in mouse model of Parkinson’s disease

BACKGROUND: Previously, we have shown that transgenic cells bearing the GDNF gene with deleted pre- and pro-regions (mGDNF) can release transgenic GDNF. The medium conditioned by transgenic cells with mGDNF induced axonal growth in rat embryonic spinal ganglion in vitro. Here we demonstrate a neurot...

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Detalles Bibliográficos
Autores principales: Revishchin, A., Moiseenko, L., Kust, N., Bazhenova, N., Teslia, P., Panteleev, D., Kovalzon, V., Pavlova, G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4902902/
https://www.ncbi.nlm.nih.gov/pubmed/27286696
http://dx.doi.org/10.1186/s12868-016-0271-x