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Effects of striatal transplantation of cells transfected with GDNF gene without pre- and pro-regions in mouse model of Parkinson’s disease
BACKGROUND: Previously, we have shown that transgenic cells bearing the GDNF gene with deleted pre- and pro-regions (mGDNF) can release transgenic GDNF. The medium conditioned by transgenic cells with mGDNF induced axonal growth in rat embryonic spinal ganglion in vitro. Here we demonstrate a neurot...
Autores principales: | Revishchin, A., Moiseenko, L., Kust, N., Bazhenova, N., Teslia, P., Panteleev, D., Kovalzon, V., Pavlova, G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4902902/ https://www.ncbi.nlm.nih.gov/pubmed/27286696 http://dx.doi.org/10.1186/s12868-016-0271-x |
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