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Developmental stage-specific effects of Pim-1 dysregulation on murine bone marrow B cell development

BACKGROUND: The serine threonine kinase Pim-1 has documented roles in hematopoietic progenitor and B cell precursor proliferation and survival. Pim-1 is a molecular target of the transcription factor Hoxa9. Previous studies showed that Pim-1 deficiency phenocopied the hematopoietic progenitor defect...

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Detalles Bibliográficos
Autores principales:	Xu, Zhihui, Gwin, Kimberly A., Li, Yulin, Medina, Kay L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4902936/ https://www.ncbi.nlm.nih.gov/pubmed/27287229 http://dx.doi.org/10.1186/s12865-016-0152-1

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