MYC and BCL2 overexpression is associated with a higher class of Memorial Sloan-Kettering Cancer Center prognostic model and poor clinical outcome in primary diffuse large B-cell lymphoma of the central nervous system

BACKGROUND: Primary diffuse large B-cell lymphoma of the central nervous system (PCNS-DLBCL) is a distinct clinicopathological entity with a poor prognosis. Concurrent MYC and BCL2 overexpression predicts inferior prognosis in systemic DLBCLs. However, the prognostic significance of MYC and BCL2 in...

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Autores principales: Kim, Sehui, Nam, Soo Jeong, Kwon, Dohee, Kim, Hannah, Lee, Eunyoung, Kim, Tae Min, Heo, Dae Seog, Park, Sung Hye, Kim, Chul Woo, Jeon, Yoon Kyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4903010/
https://www.ncbi.nlm.nih.gov/pubmed/27286976
http://dx.doi.org/10.1186/s12885-016-2397-8

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